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Amitriptyline hydrochloride, MedChemExpress

MedChemExpress Amitriptyline hydrochloride is an inhibitor of serotonin reuptake transporter (SERT) and noradrenaline reuptake transporter (NET), with Kis of 3.45 nM and 13.3 nM for human SERT and NET, respectively.

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Especificaciones

Nombre del producto químico o material Amitriptyline hydrochloride
Forma física Solid
CAS 549-18-8
Color Blanco
Notas de grado de pureza Research
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Description

Description

Amitriptyline hydrochloride also weakly binds to dopamine reuptake transporter (DAT) with a Ki of 2.58 μM. Amitriptyline hydrochloride also inhibits adrenergic, muscarinic, histamine and 5-HT receptors. Amitriptyline hydrochloride is a TrkA and TrkB receptors agonist with potent neurotrophic activity. Amitriptyline hydrochloride has antidepressant activity.
Specifications

Specifications

Amitriptyline hydrochloride
549-18-8
Research
Neuroscience-Neurodegeneration
CN(C)CC/C=C1C2=CC=CC=C2CCC3=C\1C=CC=C3.Cl
313.86
Research
Solid
Blanco
C20H24ClN
DMSO : ≥ 100 mg/mL (318.61 mM) ∣H2O : ≥ 50 mg/mL (159.31 mM)
313.86
99.56%
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Safety and Handling

Safety and Handling

H301∣H319∣H361∣H400

missing translation for 'shelfLife' : 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)

Recommended Storage : 4°C, sealed storage, away from moisture∣In solvent : -80°C, 6 months∣-20°C, 1 month (sealed storage, away from moisture)

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