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Gibco™ Human HPRG Recombinant Protein, PeproTech®
Recombinant Protein
Marca: Gibco™ 100-60-500UG
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Descripción
Recombinant Human HPRG is a 57.7 kDa glycoprotein containing 507 amino acid residues. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
HRG contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Especificaciones
| P04196 | |
| protein with no preservative | |
| 57.7 kDa | |
| 500 μg | |
| RUO | |
| AI265597; AW413091; D16jh2; D18020; DKFZp779H1622; histidine rich glycoprotein; histidine-proline-rich glycoprotein; Histidine-rich glycoprotein; histidine-rich glycoprotein 1; HPRG; HRG; HRG1; Hrgp; THPH11 | |
| HRG | |
| Unconjugated | |
| VSPTDCSAVE PEAEKALDLI NKRRRDGYLF QLLRIADAHL DRVENTTVYY LVLDVQESDC SVLSRKYWND CEPPDSRRPS EIVIGQCKVI ATRHSHESQD LRVIDFNCTT SSVSSALANT KDSPVLIDFF EDTERYRKQA NKALEKYKEE NDDFASFRVD RIERVARVRG GEGTGYFVDF SVRNCPRHHF PRHPNVFGFC RADLFYDVEA LDLESPKNLV INCEVFDPQE HENINGVPPH LGHPFHWGGH ERSSTTKPPF KPHGSRDHHH PHKPHEHGPP PPPDERDHSH GPPLPQGPPP LLPMSCSSCQ HATFGTNGAQ RHSHNNNSSD LHPHKHHSHE QHPHGHHPHA HHPHEHDTHR QHPHGHHPHG HHPHGHHPHG HHPHGHHPHC HDFQDYGPCD PPPHNQGHCC HGHGPPPGHL RRRGPGKGPR PFHCRQIGSV YRLPPLRKGE VLPLPEANFP SFPLPHHKHP LKPDNQPFPQ SVSESCPGKF KSGFPQVSMF FTHTFPK | |
| CHO cells | |
| ≥ 90% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 3273 | |
| Human HPRG | |
| CHO cells | |
| <1 EU/ μg | |
| HRG | |
| Measured by its ability to support adhesion of Con-A activated MOLT-4 cells to the Recombinant Human HPRG-coated surface. The ED50 for this effect is 1.5-2.0 ug/ml | |
| Recombinant | |
| -20°C | |
| Lyophilized |
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Título del producto
Gibco™ Human HPRG Recombinant Protein, PeproTech® > 500 μg; Unlabeled
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