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Gibco™ Human CCL21 (6Ckine) Recombinant Protein, PeproTech®
Recombinant Protein
Marca: Gibco™ 300-35A-50UG
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Descripción
Recombinant Human Exodus-2 (CCL21) is a 12.2 kDa protein containing 111 amino acid residues. *Human Exodus-2 (Catalog Number 300-35A) has replaced Human Exodus-2 (Catalog Number 300-35). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. Similar to other chemokines the protein encoded by this gene inhibits hemopoiesis and stimulates chemotaxis. This protein is chemotactic in vitro for thymocytes and activated T cells, but not for B cells, macrophages, or neutrophils. The cytokine encoded by this gene may also play a role in mediating homing of lymphocytes to secondary lymphoid organs. It is a high affinity functional ligand for chemokine receptor 7 (CCR7) that is expressed on T and B lymphocytes and a known receptor for another member of the cytokine family (small inducible cytokine A19).
Especificaciones
| O00585 | |
| protein with no preservative | |
| 12.2 kDa | |
| 50 μg | |
| RUO | |
| 6 Ckine; 6 CKBAC1; 6 CKBAC2; 6 Ckine; AI159701; ALP; AW987545; beta chemokine exodus-2; beta-chemokine exodus-2; CC chemokine 6 Ckine-ser; C-C motif chemokine 21; C-C motif chemokine 21 A; C-C motif chemokine 21 b; C-C motif chemokine 21 c; C-C motif chemokine ligand 21; CCL21; Ccl21a; Ccl21b; Ccl21c; Ccl21-leu; CCL21-Ser; chemokine (C-C motif) ligand 21; chemokine (C-C motif) ligand 21 A (serine); chemokine (C-C motif) ligand 21 B (leucine); chemokine (C-C motif) ligand 21 b (serine); chemokine (C-C motif) ligand 21 C (leucine); chemokine CCL21/6 CKINE; CKb9; ECL; Efficient Chemoattractant for Lymphocytes; exodus-2; plt; Scya21; SCYA21a; Scya21b; Scya21c; secondary lymphoid organ chemokine; secondary lymphoid tissue chemokine; Secondary lymphoid-tissue chemokine; SLC; small inducible cytokine A21; small inducible cytokine A21a; small inducible cytokine A21c; small inducible cytokine subfamily A (Cys-Cys), member 21; small-inducible cytokine A21; Small-inducible cytokine A21a; Small-inducible cytokine A21b; Small-inducible cytokine A21c; TCA4; Thymus-derived chemotactic agent 4; UNQ784/PRO1600 | |
| CCL21 | |
| Unconjugated | |
| SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCK RTERSQTPKG P | |
| E. coli | |
| ≥ 98% by SDS-PAGE gel and HPLC analyses. |
| Functional Assay | |
| 6366 | |
| Human CCL21 (6 Ckine) | |
| E. coli | |
| <1 EU/ μg | |
| CCL21 | |
| Determined by its ability to chemoattract human activated T cells cultured in the presence of IL-2. | |
| Recombinant | |
| -20°C | |
| Lyophilized |
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Título del producto
Gibco™ Human CCL21 (6Ckine) Recombinant Protein, PeproTech® > 50 μg; Unlabeled
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