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Gibco™ TrueCut™ Cas9 Protein (Prototype)
Gibco TrueCut Cas9 Protein (Prototype) is our highest performing CRISPR-Cas9 protein, engineered to deliver maximum ribonucleoprotein (RNP)-editing efficiency
Marca: Gibco™ A45221P
Descripción
- Gibco TrueCut Cas9 Protein (Prototype) is our highest performing CRISPR-Cas9 protein, engineered to deliver maximum ribonucleoprotein (RNP)-editing efficiency.
- This protein is provided here in a high-concentration, large-scale format as an early-access material for process development.
- The same high performing enzyme as our TrueCut Cas9 Protein v2, providing superior CRISPR-Cas9 editing efficiency in all tested cell lines, including primary immune cells
- Developed with protocols and demonstrated performance in editing human primary T cells
- Provided at a concentration of 10 mg/mL
- Aseptic manufacturing with sterile filling, bioburden, endotoxin, mycoplasma, residual host nucleic acids, and protein testing
- Designed to meet United States and European Pharmacopoeia standards for Ancillary Materials for Cell, Gene, and Tissue-engineered Products
- TrueCut Cas9 Protein (Prototype) is a Streptococcus pyogenes Cas9 (wt) protein, produced by recombinant DNA technology in E. coli for genome editing with CRISPR technology. Cas9 protein forms a very stable RNP complex with the guide RNA (gRNA) component of the CRISPR/Cas9 system. Incorporation of NLS aids delivery to the nucleus, increasing the editing efficiency and on-target cleavage.

Especificaciones
5 mg | |
500 μL TrueCut Cas9 Protein Prototype (10 mg/mL) Store at -15 to -25°C. |
|
Genome Editing |
Cas9 Protein | |
Dry Ice | |
TrueCut™ |
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For Research Use Only. Not for use in diagnostic procedures. Product is a prototype and performance characteristics of this product have not been established