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Gibco™ Mouse PDGF-BB Recombinant Protein, PeproTech®
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Cantidad:
1 mg
10 μg
100 μg
2 μg
250 μg
50 μg
500 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
2 microgramos
250 microgramos
50 microgramos
500 microgramos
Descripción
Recombinant Murine PDGF-BB is a 24.4 kDa disulfide-linked homodimer of two beta chains (218 total amino acids). This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
The protein encoded by this gene is a member of the platelet-derived growth factor family. The four members of this family are mitogenic factors for cells of mesenchymal origin and are characterized by a motif of eight cysteines. This gene product can exist either as a homodimer (PDGF-BB) or as a heterodimer with the platelet-derived growth factor alpha polypeptide (PDGF-AB), where the dimers are connected by disulfide bonds. Mutations in this gene are associated with meningioma. Reciprocal translocations between chromosomes 22 and 7, at sites where this gene and that for COL1A1 are located, are associated with a particular type of skin tumor called dermatofibrosarcoma protuberans resulting from unregulated expression of growth factor. Two alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

Especificaciones
Especificaciones
Número de acceso | P31240 |
Para utilizar con (aplicación) | Functional Assay |
Formulación | protein with no preservative |
ID de gen (Entrez) | 18591 |
Peso molecular | 24.4 kDa |
Nombre | Mouse PDGF-BB |
Cantidad | 100 μg |
Fuente | E. coli |
Estado normativo | RUO |
Concentración de endotoxinas | <1 EU/ μg |
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