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Invitrogen™ Mouse Leptin R ELISA Kit

Mouse Leptin R quantitates mouse Leptin R in serum, plasma, supernatant.

Marca:  Invitrogen™ EM48RBX10

3041.80 EUR hasta el 2023-03-27
Use el código promocional "20585" para aplicar la oferta.

Detalles adicionales : Peso : 2.50000kg

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Código de producto. 17854230

  • 4540.00€ / paquete de 10

Fecha estimada de envío: 21-04-2023
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Mouse Leptin R quantitates mouse Leptin R in serum, plasma, supernatant. The assay will exclusively recognize both natural and recombinant mouse Leptin R.

The leptin (OB-R) receptor is a member of the cytokine receptor superfamily which plays an important role in mammalian body weight homeostasis and energy balance. Ligand-induced activation of the OB-R by the adipose tissue-secreted hormone, leptin, appears to activate downstream signaling events through the Janus kinase (JAK)/signal transducer and activator of transcription (STAT) pathway. Leptin can homo-dimerize OB-R extracellular domains while downstream signaling events are initiated upon homo-dimerization of OB-R intracellular domains. Several isoforms of the OB-R which differ in length and signaling capabilities have been reported. RNA transcripts encoding the OB-R long form have been found in the choroid plexus and in the hypothalamus which has been proposed as a control center for satiety and energy expenditure. Mutations in either the mouse OB-R (db) or leptin (ob) genes have been shown to result in early-onset obesity. Metabolic abnormalities attributable to these genotypes include hypercorticoidemia, hyperinsulinemia and insulin resistance, hyperglycemia, altered CNS activity, reduced metabolic rate of brown adipose tissue, and a large increase in white adipose tissue.


B219; CD antigen CD295; CD295; CD295 antigen; db; diabetes; Fa; HuB219; HuB219.2; LEPR; LEP-R; Leprb; LEPRD; LEPROT; Leptin receptor; Leptin receptor (fatty); leptin receptor gene-related protein; Modb1; OB receptor; obese-like; obl; Obr; OB-R; OB-RGRP
32 pg/mL
Colorimetric Microplate Reader
Research Use Only
2°C to 8°C
1 hr 20 min
32 to 8,000 pg/mL
Pre-coated 96 well plate, Standard, Assay Diluent concentrate, Biotinylated Detection Antibody, SAV-HRP, Wash Buffer, Chromogen, Stop Solution, Adhesive Plate Covers
10 x 96 Tests
Serum, 50 μL; Plasma, 50 μL; Supernatant, 50 μL
Leptin Receptor
4 hr 45 min


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