Invitrogen™ Kit de ELISA de lisado celular LIX (CXCL5) para ratas

Descripción

The Rat LIX (CXCL5) ELISA quantitates Rt LIX in rat cell or tissue lysates. The assay will exclusively recognize both natural and recombinant Rt LIX. Principle of the method The Rat LIX solid-phase sandwich ELISA (enzyme-linked immunosorbent assay) is designed to measure the amount of the target bound between a matched antibody pair. A target-specific antibody has been pre-coated in the wells of the supplied microplate. Samples, standards, or controls are then added into these wells and bind to the immobilized (capture) antibody. The sandwich is formed by the addition of the second (detector) antibody, a substrate solution is added that reacts with the enzyme-antibody-target complex to produce measurable signal. The intensity of this signal is directly proportional to the concentration of target present in the original specimen. Rigorous validation Each manufactured lot of this ELISA kit is quality tested for criteria such as sensitivity, specificity, precision, and lot-to-lot consistency. See manual for more information on validation.

CXCL6 es una quimiotáctica para los granulocitos neutrófilos. Señala a través de la unión y la activación de sus receptores (CXCR1 y CXCR2). Además de sus propiedades quimiotácticas y angiogénicas, tiene una fuerte actividad antibacteriana contra las bacterias grampositivas y gramnegativas (90 veces superior en comparación con CXCL5 y CXCL7).