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Invitrogen™ Human Ubinuclein 2 (aa 1245-1346) Control Fragment Recombinant Protein
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Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Descripción
Highest antigen sequence indentity to the following orthologs: Mouse (89%), Rat (89%). This recombinant protein control fragment may be used for blocking experiments with the corresponding antibody, PA5-54071 (PA5-54071. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
Ubinuclein 1 (UBN1) is a ubiquitously expressed evolutionarily conserved protein which binds to proliferation-promoting genes that are repressed by formation of senescence-associated heterochromatin foci (SAHF). Ubinuclein 1 associates with various transcription factors and with histone methyltransferase activity, is indispensable for SAHF formation and appears to be a regulator of senescence. Although in most cells ubinuclein is localized to the nucleus, in cells forming tight junctions it is recruited to the cell adhesion complexes, dependently on the cell density.

Especificaciones
Especificaciones
Número de acceso | Q6ZU65 |
Concentración | ≥5.0 mg/mL |
Para utilizar con (aplicación) | Blocking Assay, Control |
Formulación | 1 M urea, PBS with no preservative; pH 7.4 |
ID de gen (Entrez) | 254048 |
Nombre | Human Ubinuclein 2 (aa 1245-1346) Control Fragment |
Cantidad | 100 μL |
Estado normativo | RUO |
Alias de gen | 2900060J04Rik; 6030408G03Rik; BC060116; D130059P03Rik; Kiaa2030; mKIAA2030; ubinuclein 1; ubinuclein 2; ubinuclein-2; UBN1; UBN2; VT; VT4 |
Nombre común | Ubinuclein 2 |
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