missing translation for 'onlineSavingsMsg'
Learn More
Learn More
STEMCELL Technologies Human Recombinant GM-CSF (E. coli-expressed)

Click to view available options
Cantidad:
1000 μg
100 μg
20 μg
500 μg
Tamaño de la unidad:
100 microgramos
1000 microgramos
20 microgramos
500 microgramos
Descripción
- Granulocyte-macrophage colony-stimulating factor (GM-CSF) promotes the proliferation and differentiation of hematopoietic progenitor cells and the generation of neutrophils, eosinophils, and macrophages
- In synergy with other cytokines such as stem cell factor, IL-3, erythropoietin, and thrombopoietin, it also stimulates erythroid and megakaryocyte progenitor cells (Barreda et al.) GM-CSF is produced by multiple cell types, including stromal cells, Paneth cells, macrophages, dendritic cells (DCs), endothelial cells, smooth muscle cells, fibroblasts, chondrocytes, and Th1 and Th17 T cells (Francisco-Cruz et al.) The receptor for GM-CSF (GM-CSFR) is composed of two subunits: the cytokine-specific α subunit (GMRα; CD116) and the common subunit βc (CD131) shared with IL-3 and IL-5 receptors (Broughton et al.) GM-CSFR is expressed on hematopoietic cells, including progenitor cells and immune cells, as well as non-hematopoietic cells
- Recombinant human GM-CSF (rhGM-CSF) promotes the production of myeloid cells of the granulocytic (neutrophils, eosinophils and basophils) and monocytic lineages in vivo
- It has been tested for mobilization of hematopoietic progenitor cells and for treating chemotherapy-induced neutropenia in patients
- GM-CSF is able to stimulate the development of DCs that ingest, process, and present antigens to the immune system (Francisco-Cruz et al.)
Especificaciones
Especificaciones
Nombre | Colony-stimulating factor 2, CSF-2, MGI-1GM, Pluripoitin-alpha |
Cantidad | 20 μg |
Tipo de célula | Dendritic Cells; Hematopoietic Stem and Progenitor Cells; Mesoderm, PSC-Derived; Monocytes; Myeloid Cells |
Grado de pureza o calidad | ≥95% |
Corrección del contenido de un producto
El Programa Encompass de Fisher Scientific ofrece artículos que no forman parte de nuestra cartera de distribución. Estos productos no suelen tener imágenes ni descripciones detalladas. Sin embargo, nos comprometemos a mejorar su experiencia de compra. Utilice el siguiente formulario para hacernos llegar sus comentarios sobre el contenido de este producto.
Título del producto
STEMCELL Technologies Human Recombinant GM-CSF (E. coli-expressed)
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido