missing translation for 'onlineSavingsMsg'
Learn More
Learn More
Invitrogen™ Human PDIR (aa 126-216) Control Fragment Recombinant Protein
Click to view available options
Cantidad:
100 μL
Tamaño de la unidad:
100 microlitros
Descripción
Highest antigen sequence indentity to the following orthologs: Mouse (91%), Rat (91%). This recombinant protein control fragment may be used for blocking experiments. In IHC/ICC and WB experiments, we recommend a 100x molar excess of the protein fragment control based on the concentration and the molecular weight. Pre-incubate the antibody-protein control fragment mixture for 30 min at room temperature.
PDIR (protein disulfide isomerase-related protein) is a novel PDI protein that was originally isolated from a human placental cDNA library. It has been suggested that from its nucleotide sequence, PDIR has three CXXC-like motifs (Cys-Ser-Met-Cys, Cys-Gly-His-Cys and Cys-Pro-His-Cys), which are found in the PDI superfamily of proteins. The CXXC motif is responsible for oxidoreductase activity. PDIR is also shown to have a putative endoplasmic reticulum (ER) retention signal 'Lys-Glu-Glu-Leu' at its carboxyl terminus, indicative of ER resident proteins. Northern blot analysis of PDIR indicates that it is preferentially expressed in cells actively secreting proteins. It has also been shown that expression of PDIR is stress-inducible. Data suggest that PDIR, like other PDIs, has oxidoreductase activity of disulfide bonds and facilitates the protein folding process within the lumen of the ER.

Especificaciones
Especificaciones
Número de acceso | Q14554 |
Concentración | ≥5.0 mg/mL |
Para utilizar con (aplicación) | Blocking Assay, Control |
Formulación | 1 M urea, PBS with no preservative; pH 7.4 |
ID de gen (Entrez) | 10954 |
Nombre | Human PDIR (aa 126-216) Control Fragment |
Cantidad | 100 μL |
Estado normativo | RUO |
Alias de gen | 2700053F16Rik; AU015525; Pdia5; PDIR; protein disulfide isomerase A5; protein disulfide isomerase associated 5; protein disulfide isomerase family A member 5; protein disulfide isomerase family A, member 5; protein disulfide isomerase-associated 5; protein disulfide isomerase-related protein; Protein disulfide-isomerase A5 |
Nombre común | PDIR |
Mostrar más |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
Invitrogen™ Human PDIR (aa 126-216) Control Fragment Recombinant Protein >
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido