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Gibco™ Human NAP-2 (CXCL7) Recombinant Protein, PeproTech®
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Cantidad:
1 mg
10 μg
100 μg
2 μg
250 μg
50 μg
500 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
2 microgramos
250 microgramos
50 microgramos
500 microgramos
Descripción
Recombinant Human NAP-2 protein is a 7.6 kDa protein containing 70 amino acid residues, including the four highly conserved cysteine residues present in CXC chemokines, and also the 'ELR' motif, common to CXC chemokines that bind to CXCR1 and CXCR2. This product is shipped at ambient temperature. For storage, handling and reconstitution information, please see the lot-specific Certificate of Analysis
Members of the a-chemokine subfamily of inducible, secreted, pro-inflammatory cytokines contain a similar motif, in which the first two cysteine residues are separated by a single residue (Cys-X-Cys), and are also chemotactic for neutrophils. The platelet basic protein (PBP), a member of the a-chemokine family, resides in the a-granules of platelets and is released upon their activation. Proteolytic cleavage of the amino terminus of PBP leads to the generation of several peptides, which include mature PBP, connective tissue-activating peptide III (CTAP III, also designated low affinity platelet factor IV (LA-PF4)), b-thromboglobulin (b-TG), and neutrophil-activating peptide 2 (NAP-2). PBP and its N-truncated derivatives mediate inflammation and wound healing. Specifically, NAP-2 activates chemotaxis and degranulation in neutrophils during inflammation. The gene encoding human PBP maps to chromosome 4q12-q13.

Especificaciones
Especificaciones
Número de acceso | P02775 |
Para utilizar con (aplicación) | ELISA, Functional Assay, Western Blot |
Formulación | protein with no preservative |
ID de gen (Entrez) | 5473 |
Peso molecular | 7.6 kDa |
Nombre | Human NAP-2 (CXCL7) |
Cantidad | 100 μg |
Fuente | E. coli |
Estado normativo | RUO |
Concentración de endotoxinas | <1 EU/ μg |
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