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ACROBiosystems Human MAG / Siglec-4a Protein, Fc Tag
362.89€ - 2661.24€
Especificaciones
Número de acceso | NP_002352.1 |
---|---|
Peso molecular | 81.1 kDa |
Fuente | Human MAG, Fc Tag (MAG-H5254) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Pro 516 (Accession # P20916-1). |
Inmunógeno | Gly 20 - Pro 516 |
Requisitos de almacenamiento | -20°C |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
16467859
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ACROBiosystems
MAG-H5254-100UG |
100 μg |
362.89€
100 microgramos |
Fecha estimada de envío: 26-04-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
16477859
|
ACROBiosystems
MAG-H5254-1MG |
1 mg |
2661.24€
1 miligramo |
Fecha estimada de envío: 26-04-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
Descripción
Myelin-associated glycoprotein (MAG), a nervous system cell adhesion molecule, is an I-type lectin that binds to sialylated glycoconjugates, including gangliosides bearing characteristic structural determinants. Preferentially binds to alpha-2,3-linked sialic acid. Binds ganglioside Gt1b. Adhesion molecule that mediates interactions between myelinating cells and neurons by binding to neuronal sialic acid-containing gangliosides and to the glycoproteins RTN4R and RTN4RL2. Protection against apoptosis is probably mediated via interaction with neuronal RTN4R and RTN4RL2. In dorsal root ganglion neurons the inhibition is mediated primarily via binding to neuronal RTN4R or RTN4RL2 and to a lesser degree via binding to neuronal gangliosides. In cerebellar granule cells the inhibition is mediated primarily via binding to neuronal gangliosides. In sensory neurons, inhibition of neurite extension depends only partially on RTN4R, RTN4RL2 and gangliosides.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 81.1 kDa. The protein migrates as 100-115 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
NP_002352.1 | |
Human MAG, Fc Tag (MAG-H5254) is expressed from human 293 cells (HEK293). It contains AA Gly 20 - Pro 516 (Accession # P20916-1). | |
-20°C | |
MAG / Siglec-4 A | |
Human | |
PBS, pH7.4 | |
HEK293 | |
Bio-Markers and CD Antigens |
81.1 kDa | |
Gly 20 - Pro 516 | |
MAG,Siglec-4 A,GMA,S-MAG | |
Unconjugated | |
Fc Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>95% as determined by SDS-PAGE |