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Invitrogen™ Human FLT1 (VEGFR1), GST Tag Recombinant Protein

Recombinant Protein

2165.00€ - 13870.00€

Specifications

Número de acceso P17948
Concentración See Label
Para utilizar con (aplicación) Kinase Assay
Formulación 50 mM tris with 0.02% Triton X-100, 0.5 mM EDTA, 150 mM NaCl, 2 mM DTT, 50% glycerol and no preservative; pH 7.5
ID de gen (Entrez) 2321
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Products 2
Product Code Brand Cantidad Price Quantity & Availability  
Product Code Brand Cantidad Price Quantity & Availability  
15488483
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Invitrogen™
PR6731B
100 μg
2165.00€
100 microgramos
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10087082
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Invitrogen™
PR6731A
1 mg
13870.00€
1 miligramo
Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Description

Description

For maximum recovery please spin prior to use. Unless noted below, aliquots of the 5 μg, 10 μg and 20 μg sizes of kinase are not recommended as materials can be used in original packaging until exhausted. For larger sizes, the number of freeze/thaws may be reduced by preparing aliquots, aliquots below 20 μL are not recommended. Please never store a kinase diluted. If properly stored at -80C, this product is guaranteed for 6 months from date of purchase. Protein Form: Cytoplasmic

FLT1 (VEGFR1) is a receptor tyrosine kinase which plays a critical role in angiogenesis. Active angiogenesis has been found to play important role in many pathological and physiological processes, such as tumor progression, diabetic retinopathy, rheumatoid arthritis and wound healing. May play an essential role as a negative regulator of embryonic angiogenesis by inhibiting excessive proliferation of endothelial cells. Can promote endothelial cell proliferation, survival and angiogenesis in adulthood. Its function in promoting cell proliferation seems to be cell-type specific. Promotes PGF-mediated proliferation of endothelial cells, proliferation of some types of cancer cells, but does not promote proliferation of normal fibroblasts (in vitro). Has very high affinity for VEGFA and relatively low protein kinase activity; may function as a negative regulator of VEGFA signaling by limiting the amount of free VEGFA and preventing its binding to KDR.
Specifications
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Invitrogen™ Human FLT1 (VEGFR1), GST Tag Recombinant Protein

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