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CD138 (Syndecan-1) Mouse, anti-Human, PE, Clone: MI15, STEMCELL Technologies
Mouse Monoclonal Antibody
Marca: Stemcell Technologies 60003PE
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Descripción
- The MI15 antibody reacts with an extracellular epitope on CD138 (Syndecan-1), an ∼85 - 95 kDa type 1 transmembrane glycoprotein expressed on the surface of pre-B cells, immature B cells, and normal and malignant plasma cells (but not mature circulating B cells), as well as on non-hematopoietic cells such as embryonic mesenchymal cells, endothelial, epithelial and neural cells
- CD138 expression is used as a diagnostic marker for several types of tumors
- CD138 is thought to act primarily as a receptor that modulates cell proliferation, cell migration and cell-matrix associations by linking the extracellular matrix to the cytoskeleton
- Theparin sulfate and chondroitin sulfate moieties attached to CD138 associate with several proteins, including collagens, fibronectin, tenascin, thrombospondin and certain cytokines
- The MI15 antibody recognizes a different epitope than that of the clone DL-101 anti-CD138 antibody but blocks binding of clone B-B4
Especificaciones
| CD138 (Syndecan-1) | |
| Monoclonal | |
| PE | |
| 100 Tests | |
| Cynomolgus, Human, Rhesus Monkey | |
| B Cells, Plasma |
| Immunohistochemistry, Western Blot, Flow Cytometry, Immunocytochemistry, Immunofluorescence | |
| MI15 | |
| Mouse | |
| Primary | |
| IgG1 κ |
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Título del producto
CD138 (Syndecan-1) Mouse, anti-Human, PE, Clone: MI15, STEMCELL Technologies
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