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Cardiac Troponin I Mouse anti-Human, Mouse, Rat, Clone: 1D5D6, Proteintech
Mouse Monoclonal Antibody
145.00€ - 410.00€
Especificaciones
Antígeno | Cardiac Troponin I |
---|---|
Clon | 1D5D6 |
Concentración | 1 mg/mL |
Aplicaciones | Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence |
Clasificación | Monoclonal |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
16878195
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Proteintech
66376-1-IG-20UL |
20 μL |
145.00€
20 microlitros |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | |||||
16868195
|
Proteintech
66376-1-IG-150UL |
150 μL |
410.00€
150 microlitros |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | |||||
Descripción
This antibody is specific to cTnI, but not cross-react with skeletal TnI.
Cardiac Troponin I (Cardiac-specific troponin I, TnI, Troponin I) is an integral inhibitory protein in cardiac muscle that exists as part of a complex with troponin C (TnC) and troponin T (TnT). The TnT subunit of troponin binds to tropomyosin-t form, a troponin-tropomyosin complex, anchored in place by the binding of TnI to actin, within muscle thin filaments. Structural change resulting from the binding of calcium to specific sites on the regulatory TnC subunit, releases the inhibitory region of TnI from actin, anabling the attachment of the molecular motor protein myosin, allowing for muscle contraction and hence movement. The measurements of blood TnI and TnT levels is an important diagnostics indicator of heart muscle damage, and can be used to differentiate between angina and myocardial infarction in patients with chest pains. Cardiac Troponin I has also been shown to inhibit angiogenesis in vivo and in vitro. Mutations in the Cardiac Troponin I gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM).Especificaciones
Cardiac Troponin I | |
1 mg/mL | |
Monoclonal | |
Liquid | |
RUO | |
PBS with 50% glycerol and 0.02% sodium azide; pH 7.3 | |
Cardiac troponin I, CMD2A, CMH7, cTnI, RCM1, TNNC1, TNNI3, troponin I type 3 (cardiac), Troponin I, cardiac muscle | |
TNNI3 | |
IgG1 | |
Protein G | |
Antibody |
1D5D6 | |
Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot, Immunofluorescence | |
Unconjugated | |
Mouse | |
Rat, Mouse, Human | |
P19429, P23693, P48787 | |
21954, 29248, 7137 | |
Cardiac Troponin I Fusion Protein Ag16758 | |
Primary | |
-20°C | |
TNNI3 |
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Título del producto
Cardiac Troponin I Mouse anti-Human, Mouse, Rat, Clone: 1D5D6, Proteintech