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CD11b/Mac-1 Mouse anti-Human, Alexa Fluor 488, Clone: ICRF44, BD
Mouse Monoclonal Antibody
Marca: BD Biosciences 557701
268.98 EUR hasta el 2025-12-31
Use el código promocional "25339" para aplicar la oferta.
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Descripción
The ICRF44 monoclonal antibody specifically binds to CD11b, the 165-kDa adhesion glycoprotein that associates with the 95-kDa integrin β2 (CD18) to form the CD11b/CD18 complex, also known as Mac-1 or CR3. CD11b is expressed on activated lymphocytes, monocytes, granulocytes, and a subset of NK cells. CD11b functions in cell-cell and cell-substrate interactions and is a receptor for iC3b, CD54 (ICAM-1), CD102 (ICAM-2) and CD50 (ICAM-3). This antibody significantly inhibits polymorphonuclear leukocyte aggregation in response to fMLP.
This antibody is routinely tested by flow cytometric analysis. Other applications were tested at BD Biosciences Pharmingen during antibody development only or reported in the literature.
Especificaciones
| CD11b | |
| Monoclonal | |
| Alexa Fluor 488 | |
| Aqueous buffered solution containing BSA and ≤0.09% sodium azide. | |
| Human monocytes | |
| 100 Tests | |
| Immunology | |
| Human | |
| IgG1 κ |
| Flow Cytometry | |
| ICRF44 | |
| Mac-1α, integrin αM subunit, CR3 α chain | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
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Título del producto
CD11b/Mac-1 Mouse anti-Human, Alexa Fluor 488, Clone: ICRF44, BD > 100 Tests; Alexa Fluor 488
For Research Use Only.
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