missing translation for 'onlineSavingsMsg'
Learn More
Learn More
SHISA4 Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA5121851
Este artículo no se puede devolver.
Vea la política de devoluciones
Descripción
SHISA4 plays an essential role in the maturation of presomitic mesoderm cells by individual attenuation of both FGF and WNT signaling. The Shisa family of single-transmembrane proteins is characterized by an N-terminal cysteine-rich domain and a proline-rich C-terminal region. Its founding member, Xenopus Shisa, promotes head development by antagonizing Wnt and FGF signaling. Shisa physically interacted with immature forms of the Wnt receptor Frizzled and the FGF receptor within the ER and inhibited their posttranslational maturation and trafficking to the cell surface. Loss of Shisa function sensitized the neuroectoderm to Wnt signaling and suppressed head formation during gastrulation.
Especificaciones
| SHISA4 | |
| Polyclonal | |
| Unconjugated | |
| SHISA4 | |
| 9330132O05Rik; C1orf40; mShisa4; Protein shisa-4; shisa family member 4; shisa homolog 4; SHISA4; Tmem58; transmembrane protein 58; UNQ583/PRO1153 | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 149345, 77552 | |
| -20°C | |
| Liquid |
| Western Blot | |
| 0.5 mg/mL | |
| PBS with 50% glycerol and 0.05% ProClin 300 | |
| Q8CA71, Q96DD7 | |
| SHISA4 | |
| Gly28-Ala197 (Accession Q96DD7), with N-terminal His Tag | |
| 100 μL | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG |
Corrección del contenido de un producto
Proporcione sus comentarios sobre el contenido del producto rellenando el siguiente formulario.
Título del producto
SHISA4 Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
¿Detecta una oportunidad de mejora?Comparta una corrección de contenido