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RUNX3 Monoclonal Antibody (2B3), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA517169
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Descripción
MA5-17169 targets RUNX3 in indirect ELISA, FACS, ICC, IHC, IF and WB applications and shows reactivity with Human and Mouse samples. The MA5-17169 immunogen is purified recombinant fragment of human RUNX3 (amino acids:186-252) expressed in E. Coli. MA5-17169 detects RUNX3 which has a predicted molecular weight of approximately 44.4kDa.
This gene encodes a member of the runt domain-containing family of transcription factors. A heterodimer of this protein and a beta subunit forms a complex that binds to the core DNA sequence 5'-PYGPYGGT-3' found in a number of enhancers and promoters, and can either activate or suppress transcription. It also interacts with other transcription factors. It functions as a tumor suppressor, and the gene is frequently deleted or transcriptionally silenced in cancer. Multiple transcript variants encoding different isoforms have been found for this gene.
Especificaciones
| RUNX3 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 0.05% sodium azide | |
| Q13761, Q64131 | |
| RUNX3 | |
| Purified recombinant fragment of human RUNX3 (amino acids:186-252) expressed in E. Coli. | |
| 100 μg | |
| Primary | |
| Human, Mouse | |
| Antibody | |
| IgG2b |
| ChIP Assay, ELISA, Flow Cytometry, Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| 2B3 | |
| Unconjugated | |
| RUNX3 | |
| Acute myeloid leukemia 2 protein; acute myeloid leukemia gene 2; AML2; CBFA3; CBF-alpha 3; CBF-alpha-3; core binding factor alpha 3; core-binding factor subunit alpha-3; core-binding factor, runt domain, alpha subunit 3; oncogene AML-2; PEA2 alpha C; PEA2-alpha C; PEBP2 alpha C; PEBP2A3; PEBP2aC; PEBP2-alpha C; polyomavirus enhancer-binding protein 2 alpha C subunit; runt domain, alpha subunit 3; Runt related transcription factor 3; runt-related transcription factor 3; RUNX3; SL3/AKV core-binding factor alpha C subunit; SL3-3 enhancer factor 1 alpha C subunit; transcription factor AML2; transcription factor AML2/CBFA3 | |
| Mouse | |
| Protein G | |
| RUO | |
| 12399, 864 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| Liquid |
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Título del producto
RUNX3 Monoclonal Antibody (2B3), Invitrogen™ > 100 μg; Unconjugated
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