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Phospho-c-Jun (Thr239) Polyclonal Antibody, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen PA540193
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Descripción
This antibody is predicted to react with mouse and rat based on sequence homology.
c-Jun is a transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. It promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation. Involved in activated KRAS-mediated transcriptional activation of USP28 in colorectal cancer (CRC) cells.
Especificaciones
| Phospho-c-Jun (Thr239) | |
| Polyclonal | |
| Unconjugated | |
| JUN | |
| Activator protein 1; AH119; AP1; AP-1; Avian sarcoma virus 17 (v-jun) oncogene homolog; cjun; c-Jun; c-jun transcription factor; enhancer-binding protein AP1; I79_009953; immediate early; JUN; Jun A; Jun activation domain binding protein; Jun oncogene; jun proto-oncogene; Jun proto-oncogene, AP-1 transcription factor subunit; Junc; JUND; p39; proto-oncogene c-Jun; Rjg-9; transcription factor; transcription factor AP-1; V-jun avian sarcoma virus 17 oncogene homolog; v-jun sarcoma virus 17 oncogene homolog | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 16476, 24516, 3725 | |
| -20° C, Avoid Freeze/Thaw Cycles | |
| Liquid |
| ELISA, Immunohistochemistry, Immunoprecipitation, Western Blot | |
| 1 mg/mL | |
| PBS with 0.5% BSA, 50% glycerol and 0.02% sodium azide; pH 7.4 | |
| P05412, P05627, P17325 | |
| JUN | |
| Synthesized peptide derived from human AP-1 around the phosphorylation site of T239. | |
| 100 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Antibody | |
| IgG |
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Título del producto
Phospho-c-Jun (Thr239) Polyclonal Antibody, Invitrogen™ > 100 μL; Unconjugated
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