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Invitrogen™ Mouse SCF, AOF Recombinant Protein
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Cantidad:
100 μg
10 μg
1 mg
500 μg
Tamaño de la unidad:
1 miligramo
10 microgramos
100 microgramos
500 microgramos
Descripción
Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.
- Purity: >95% by SDS-Page
- Endotoxin Concentration: AX41 ≤EUs/μg
- Protein Length: 165 aa.
- Biological Activity: <20 ng/mL
- Molecular Weight: 18.4 kDa
- Animal Origin Free: Yes
Especificaciones
Especificaciones
| Número de acceso | P20826 |
| Para utilizar con (aplicación) | Control, ELISA, Functional Assay, Gel Shift, Western Blot |
| Formulación | 20 mM sodium phosphate with no preservative |
| ID de gen (Entrez) | 17311 |
| Peso molecular | 18.4 kDa |
| Nombre | Mouse Stem Cell Factor (SCF), AOF |
| Cantidad | 100 μg |
| Fuente | E. coli |
| Requisitos de almacenamiento | -20°C |
| Estado normativo | RUO |
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Título del producto
Invitrogen™ Mouse SCF, AOF Recombinant Protein >
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