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Invitrogen™ Mouse SCF, AOF Recombinant Protein
E. coli Recombinant Protein
210.00€ - 2965.00€
Especificaciones
| Número de acceso | P20826 |
|---|---|
| Para utilizar con (aplicación) | Control, ELISA, Functional Assay, Gel Shift, Western Blot |
| Formulación | 20 mM sodium phosphate with no preservative |
| ID de gen (Entrez) | 17311 |
| Peso molecular | 18.4 kDa |
Descripción
Stem cell factor (SCF) is the ligand of the c-Kit oncogene and is expressed by various structural and inflammatory cells in the airways. Binding of SCF by the c-Kit receptor leads to homodimerization of the receptor and the activation of signalling pathways such as PI-3, PLC-gamma, Jak/STAT, and MAP kinase pathways. SCF expression leads to the induction of mast cell survival and the expression and release of histamine, pro-inflammatory cytokines and chemokines. The inhibition of the SCF/c-Kit pathway leads to a decrease in histamine levels, mast cell and eosinophil infiltration, IL-4 production and airway hyperresponsiveness, suggesting this pathway may be a useful therapeutic target in inflammatory diseases such as asthma. At least two isoforms of SCF are known to exist.- Purity: >95% by SDS-Page
- Endotoxin Concentration: AX41 ≤EUs/μg
- Protein Length: 165 aa.
- Biological Activity: <20 ng/mL
- Molecular Weight: 18.4 kDa
- Animal Origin Free: Yes
Especificaciones
| P20826 | |
| 20 mM sodium phosphate with no preservative | |
| 18.4 kDa | |
| E. coli | |
| RUO | |
| Kitl | |
| Unconjugated | |
| Lyophilized |
| Control, ELISA, Functional Assay, Gel Shift, Western Blot | |
| 17311 | |
| Mouse Stem Cell Factor (SCF), AOF | |
| -20°C | |
| 710-712; blz; c-Kit ligand; Clo; cloud gray; Con; contrasted; CSF; DCUA; DFNA69; DKFZp686F2250; familial progressive hyperpigmentation 2; FPH2; FPHH; Gb; grizzle-belly; Hematopoietic growth factor KL; H-SCF; Kit ligand; Kitl; Kitlg; kit-ligand; KL-1; Mast cell growth factor; MGF; M-SCF; Processed kit ligand; SCF; SF; SHEP7; sKITLG; Sl; Slf; Soluble KIT ligand; Steel factor; steel factor/kit ligand; Stem cell factor; stem cell factor KL-1; stem cell factor, CSF | |
| Mouse | |
| Recombinant | |
| >95% |
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Título del producto
Invitrogen™ Mouse SCF, AOF Recombinant Protein