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![Invitrogen™ LRRK2 [G2019S] Recombinant Protein 1mg](https://assets.fishersci.com/TFS-Assets/LSG/product-images/Cell_Bio_Rec_Prot_Invitrogen_Vial.jpg-650.jpg)
Invitrogen™ LRRK2 [G2019S] Recombinant Protein
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene, which codes for a multidomain protein kinase, are considered the most common genetic cause of late-onset autosomal-dominant Parkinson's disease.
Marca: Invitrogen™ A15202
Detalles adicionales : Peso : 0.01000kg
Descripción
This full-length, purified and active LRRK2 G2019S mutant protein may be useful in research to better understand the most common Parkinson's disease-relevant mutant, as well as to explore the mechanisms underlying the disease.
- Increase disease relevance by interrogating a purified and active full-length LRRK2 protein
- Uncover novel compounds or hits specific to the full-length form
- Advance Parkinson 's research using the full-length protein and validated assays
Especificaciones
| NP_940980.3 | |
| 288 kDa | |
| AURA17, DARDARIN, PARK8, RIPK7, ROCO2 | |
| Human | |
| Store at -68 to -85°C. Aliquot at first use to avoid multiple freeze-thaws. If properly stored, this product is guaranteed for 6 months from date of purchase. Suspended in: 50 mM Tris (pH 7.5), 150 mM NaCl, 0.5 mM EDTA, 0.02% Triton™X–100, 2 mM DTT, and 50% glycerol. |
|
| Kinases & Inhibitors | |
| Liquid |
| Kinase Assay | |
| 1mg | |
| LRRK Kinase Family | |
| DYKDDDDK | |
| Mammalian | |
| Recombinant, Full Length, Mutant | |
| Neurobiology |