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IL-5 Monoclonal Antibody (C1), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA551008
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Descripción
IL-5 is a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. IL-5 cytokine is a main regulator of eosinopoiesis, eosinophil maturation and activation. The elevated production of this cytokine is reported to be related to asthma or hypereosinophilic syndromes. The receptor of IL-5 cytokine is a heterodimer, whose beta subunit is shared with the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). IL-5, together with those for interleukin 4 (IL4), interleukin 13 (IL13), and CSF2, form a cytokine gene cluster on chromosome 5. IL-5, IL4, and IL13 are found to be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.
Especificaciones
| IL-5 | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with 50% glycerol and 0.05% Proclin 300, pH 7.4 | |
| P04401, P05113, Q08125 | |
| Il5 | |
| Recombinant Human IL5 protein, Ile20-Ser134 (Accession #P05113) | |
| 20 μL | |
| Primary | |
| Human, Mouse, Rat | |
| Liquid |
| Immunocytochemistry, Immunohistochemistry (Paraffin), Western Blot | |
| C1 | |
| Unconjugated | |
| Il5 | |
| B-cell differentiation factor I, B-cell growth factor II, BCGF-II, colony-stimulating factor, eosinophil, cytotoxic T-lymphocyte inducer, EDF, Eosinophil differentiation factor, IL5, IL-5, ILN, Interleukin, Interleukin 5, Interleukin 5 (colony-stimulating factor eosinophil), Interleukin 5 (colony-stimulating factor, eosinophil), Interleukin5, interleukin-5, T-cell replacing factor, TRF | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 16191, 24497, 3567 | |
| Store at 4°C short term. For long term storage, store at -20°C, avoiding freeze/thaw cycles. | |
| IgG1 κ |
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Título del producto
IL-5 Monoclonal Antibody (C1), Invitrogen™ > 20 μL; Unconjugated
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