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STEMCELL Technologies Human Recombinant IFN-gamma, ACF

Interferon-gamma, animal component-free

Marca:  STEMCELL Technologies 78141.1

Detalles adicionales : Peso : 0.00110kg

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Código de producto. 17199661

  • 276.64€ / 100 microgramos
Fecha estimada de envío: 17-11-2022
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Descripción

Descripción

  • Interferon-gamma (IFN-γ), also known as type II interferon, is produced by T and NK cells, and in smaller amounts by dendritic cells and macrophages
  • IFN-γ is controlled by cytokines such as IL-12 and IL-18 secreted in response to infection
  • IFN-γ binds to a receptor complex and initiates signal transduction via the JAK/STAT pathway; this culminates in the transcription and activation of many genes that control a diverse array of immunological functions
  • IFN-γ stimulates the antimicrobial and anti-tumor activity of macrophages, NK cells, and neutrophils by promoting the activation of microbial effector functions such as production of reactive oxygen species, NO intermediates, and complement
  • IFN-γ enhances MHC class I and II expression in dendritic cells and mononuclear phagocytes, as well as the production of IL-12 by dendritic cells
Especificaciones

Especificaciones

Interferon gamma, Type II interferon
≥95%
100 μg
B Cells; Hematopoietic Stem and Progenitor Cells; Intestinal Cells; Mesenchymal Stem and Progenitor Cells; T Cells
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Ofertas especiales

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