missing translation for 'onlineSavingsMsg'
Learn More
Learn More
STEMCELL Technologies Human Recombinant GDNF
Glial cell line-derived neurotrophic factor
Brand: STEMCELL Technologies 78058.1
Additional Details : Peso : 0.00110kg
Description
- Glial cell line-derived neurotrophic factor (GDNF) is a neurotrophic factor and a member of the tumor growth factor (TGF)-beta superfamily
- The GDNF family of growth factors also includes neurturin, persephin, and artemin, which have seven conserved cysteine residues called cysteine-knots
- GDNF family ligands signal through binding to specific GDNF-family receptor-α (GFRα) co-receptors and activate the RET receptor tyrosine kinase
- Four different forms of GFRα co-receptors have been characterized (GFRα 1-4); GDNF binds specifically to GFRα1 prior to forming a complex with RET (Airaksinen & Saarma)
- GDNF, together with Human Recombinant BDNF (Catalog #78005), BrainPhys™ Neuronal Medium (Catalog #05790), and other supplements, can be used to differentiate human pluripotent stem cell (hPSC)-derived neural progenitor cells into neurons
Specifications
| Astrocyte-derived trophic factor, ATF, ATF1, ATF2, Glial cell-derived neurotrophic factor | |
| 100 μg | |
| Neural Cells, PSC-Derived; Neural Stem and Progenitor Cells; Neurons | |
| ≥95% |