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ACROBiosystems Human NRG1 Beta 1 Protein, Fc Tag

Marca:  ACROBiosystems NR1-H5268-100ug

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 17186551

  • 342.14€ / 100 microgramos
Fecha estimada de envío: 20-10-2022
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Descripción

Descripción

NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.

This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 53.2 kDa. The protein migrates as 65-80 kDa and 90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_039250.2
53.2 kDa
100 µg
Ser 2 - Lys 246
NRG1 Beta 1,HRG1 beta 1,Neuregulin-1 beta 1,Neuregulin1 beta 1,NRG1,ARIA,GGF,HGL,HRGA,NDF,SMDF
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>90% as determined by SDS-PAGE
Human NRG1 Beta 1, Fc Tag (NR1-H5268) is expressed from human 293 cells (HEK293). It contains AA Ser 2 - Lys 246 (Accession # Q02297-6).
-20°C
NRG1 Beta 1
Fc Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
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Ofertas especiales

Ofertas especiales