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ACROBiosystems Human NRG1 Beta 1 Protein, Fc Tag
en la oferta
Especificaciones
| Número de acceso | NP_039250.2 |
|---|---|
| Peso molecular | 53.2 kDa |
| Fuente | Human NRG1 Beta 1, Fc Tag (NR1-H5268) is expressed from human 293 cells (HEK293). It contains AA Ser 2 - Lys 246 (Accession # Q02297-6). |
| Inmunógeno | Ser 2 - Lys 246 |
| Requisitos de almacenamiento | -20°C |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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17186551
|
ACROBiosystems
NR1-H5268-100UG |
100 μg |
en la oferta
100 microgramos |
N/A | Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
Este artículo requiere una actualización de precios antes de ser solicitado. Solicite el precio de este artículo aquí. |
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17196551
|
ACROBiosystems
NR1-H5268-1MG |
1 mg |
en la oferta
1 miligramo |
N/A | Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
|
Este artículo requiere una actualización de precios antes de ser solicitado. Solicite el precio de este artículo aquí. |
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Descripción
NRG1 is one of four proteins in the neuregulin family that act on the EGFR family of receptors. It is known that an extraordinary variety of different isoforms are produced from the NRG1 gene by alternative splicing. These isoforms include heregulins (HRGs), glial growth factors (GGFs) and sensory and motor neuron-derived factor (SMDF). They are tissue-specific and differ significantly in their structure. The HRG isoforms all contain immunoglobulin (Ig) and epidermal growth factor-like (EGF-like) domains. GGF and GGF2 isoforms contain a kringle-like sequence plus Ig and EGF-like domains; and the SMDF isoform shares only the EGF-like domain with other isoforms. The receptors for all NRG1 isoforms are the ERBB family of tyrosine kinase transmembrane receptors. Through their displayed interaction with ERBB receptors, NRG1 isoforms induce the growth and differentiation of epithelial, neuronal, glial, and other types of cells.
This protein carries a human IgG1 Fc tag at the N-terminus. The protein has a calculated MW of 53.2 kDa. The protein migrates as 65-80 kDa and 90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
| NP_039250.2 | |
| Human NRG1 Beta 1, Fc Tag (NR1-H5268) is expressed from human 293 cells (HEK293). It contains AA Ser 2 - Lys 246 (Accession # Q02297-6). | |
| -20°C | |
| NRG1 Beta 1 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |
| 53.2 kDa | |
| Ser 2 - Lys 246 | |
| NRG1 Beta 1,HRG1 beta 1,Neuregulin-1 beta 1,Neuregulin1 beta 1,NRG1,ARIA,GGF,HGL,HRGA,NDF,SMDF | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >90% as determined by SDS-PAGE |