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ACROBiosystems Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag
Marca: ACROBiosystems MU1-H5256-100ug
Detalles adicionales : Peso : 0.00010kg
Descripción
Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.7 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
| NP_002447.4 | |
| 100 μg | |
| Ser 116 - Gly 173 | |
| Mucin 1,MUC1,CD227,EMA,H23AG,KL-6,MAM6,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,CA 15-3,Episialin | |
| Unconjugated | |
| Fc Tag | |
| Less than 1.0 EU / μg by the LAL method. | |
| Powder | |
| >95% as determined by SDS-PAGE |
| 32.7 kDa | |
| Human Mucin-1 (116-173), Fc Tag (MU1-H5256) is expressed from human 293 cells (HEK293). It contains AA Ser 116 - Gly 173 (Accession # P15941-8). | |
| -20°C | |
| Mucin-1 | |
| Human | |
| PBS, pH7.4 | |
| HEK293 | |
| Bio-Markers and CD Antigens |