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ACROBiosystems Human Mucin-1 / MUC-1 (116-173) Protein, Fc Tag

Marca:  ACROBiosystems MU1-H5256-1mg

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 17186511

  • 2896.79€ / 1 miligramo
Fecha estimada de envío: 20-10-2022
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Descripción

Descripción

Membrane mucins have several functions in epithelial cells including cytoprotection, extravasation during metastases, maintenance of luminal structure, and signal transduction. MUC17, contains an extended, repetitive extracellular glycosylation domain and a carboxyl terminus with two EGF-like domains, a SEA module domain, a transmembrane domain, and a cytoplasmic domain with potential serine and tyrosine phosphorylation sites. Interacts via its C-terminus with PDZK1 and this interaction appears important for proper localization. Probably plays a role in maintaining homeostasis on mucosal surfaces.

This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 32.7 kDa. The protein migrates as 40-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_002447.4
32.7 kDa
1 mg
Ser 116 - Gly 173
Mucin 1,MUC1,CD227,EMA,H23AG,KL-6,MAM6,MUC-1/SEC,MUC-1/X,MUC1/ZD,PEM,PEMT,PUM,CA 15-3,Episialin
Unconjugated
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Human Mucin-1 (116-173), Fc Tag (MU1-H5256) is expressed from human 293 cells (HEK293). It contains AA Ser 116 - Gly 173 (Accession # P15941-8).
-20°C
Mucin-1
Fc Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
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