Dengue Virus Type 1-4 NS1 Monoclonal Antibody (5165), Invitrogen™

Descripción

Specificity: Specific for the NS1 protein of all 4 serotypes. Best ELISA pairs (capture/conjugate): Dengue Virus Type 1-4 NS1 Monoclonal antibody (Product # MA5-47551)/Dengue Virus Type 1-4 NS1 Monoclonal antibody (Product # MA5-47554). Purified preparations consist of >90% pure mouse monoclonal antibody which has been purified from ascites fluid by protein A chromatography. The final preparation is formulated to a protein concentration of 100 μg/mL in 0.01 M phosphate buffered saline, pH 7.2 and contains 0.1% sodium azide. Each vial contains 1.0 mL. This product contains no stabilizing proteins and should be stored at 4C until ready for use. Working dilution must be determined by the user. Suggested starting ranges are 1:10-1:50 for ICC/IF and 1:20-1:200. for ELISA.

Dengue fever and dengue hemorrhagic fever are acute febrile diseases, found in the tropics and Africa. Caused by one of four closely related virus serotypes of the genus Flavivirus, family Flaviviridae, each serotype is sufficiently different that there is no cross-protection and epidemics caused by multiple serotypes (hyperendemicity) can occur. Dengue is transmitted to humans by the Aedes aegypti (rarely Aedes albopictus) mosquito, which feeds during the day.