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ACROBiosystems Cynomolgus GUCY2C / Guanylyl cyclase C Protein, His Tag

399.17€ - 2896.79€

Especificaciones

Número de acceso XP_005570270.1
Formato Powder
Peso molecular 48.0 kDa
Pureza >90% as determined by SDS-PAGE
Fuente Cynomolgus GUCY2C, His Tag (GUC-C52H6) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Gln 430 (Accession # XP_005570270.1).
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Productos 2
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
Código de producto Marca Cantidad Precio Cantidad y disponibilidad  
17186341
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ACROBiosystems
GUC-C52H6-1MG
1 mg
2896.79€
1 miligramo
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Fecha estimada de envío: 05-01-2023
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17176341
Ver documentos Detalles de la promoción
ACROBiosystems
GUC-C52H6-100UG
100 µg
399.17€
100 microgramos
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»
Fecha estimada de envío: 05-01-2023
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Por favor, para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo.
Descripción

Descripción

GUCY2C (Guanylyl Cyclase C), also known as heat-stable enterotoxin receptor, is a type I transmembrane protein of the guanylate cyclase (gc) family that signal by producing cGMP. Guanylate cyclase C (GUCY2C) and its hormones guanylin and uroguanylin have recently emerged as one paracrine axis defending intestinal mucosal integrity against mutational, chemical, and inflammatory injury. GUCY2C murine CAR-T cells recognized and killed human colorectal cancer cells endogenously expressing GUCY2C. Thus, we have identified a human GUCY2C-specific CAR-T cell therapy approach that may be developed for the treatment of GUCY2C-expressing metastatic colorectal cancer.

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 48.0 kDa. The protein migrates as 60-90 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

XP_005570270.1
48.0 kDa
Cynomolgus GUCY2C, His Tag (GUC-C52H6) is expressed from human 293 cells (HEK293). It contains AA Ser 24 - Gln 430 (Accession # XP_005570270.1).
-20°C
GUCY2C
His Tag
Less than 1.0 EU / µg by the LAL method.
Bio-Markers and CD Antigens
Powder
>90% as determined by SDS-PAGE
Ser 24 - Gln 430
GUCY2C,GUC2C,STAR,STA receptor,hSTAR,GC-C
Unconjugated
PBS, pH7.4
HEK293
Cynomolgus
SDS
Product Certifications