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Thermo Scientific™ CellSensor™ TNFa-bla THP-1 Cell Line
Tumor necrosis factor-alpha (TNFα) cytokine cell signaling is a critical pathway involved in immune and inflammatory responses. In addition, TNFα has been shown to inhibit growth and induce differentiation in tumor and non-tumor cells.
Marca: Thermo Scientific™ K1672B
Descripción
Tumor necrosis factor-alpha (TNFα) cytokine cell signaling is a critical pathway involved in immune and inflammatory responses. In addition, TNFα has been shown to inhibit growth and induce differentiation in tumor and non-tumor cells. The CellSensor™ TNFα-bla THP-1 cell line is a suspension cell line derived from human acute monocytic leukemia cells. The TNFα-bla THP-1 cell line is used to measure the TNFα cytokine signaling pathway via transcriptional regulation of the beta-lactamase gene. This cell line was constructed using GenomeScreen™ technology utilizing a promoterless beta-lactamase reporter gene randomly integrated into the genome of the THP-1 cell line. Sequential rounds of sorting were performed to isolate cell clones containing tagged genes induced by TNFα. These cells have been shown to be responsive to TNFa agonist. Academic and non-profit customers, please inquire for special pricing.

Especificaciones
Células divisoras | |
Citocinas, vía de señalización | |
Células en proceso de división | |
Ruta de señalización |
Las líneas de células CellSensor™ se envían en hielo seco. Se debe almacenar en nitrógeno líquido inmediatamente después de su recepción, o descongelar para su uso inmediato. | |
1 viales | |
CellSensor™ |
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Para uso exclusivo en investigación. No apto para uso en procedimientos diagnósticos.