Invitrogen™ CDKL5 Recombinant Human Protein
This CDKL5 Recombinant Human Protein (1-498) was expressed in insect cells.
Marca: Invitrogen™ A33353
Detalles adicionales : Peso : 0.00900kg
DescripciónCDKL5 serine/threonine kinase (STK9) is associated with X-linked infantile spasm syndrome (ISSX), also known as X-linked West syndrome and Rett syndrome (RTT). CDKL5 can control nuclear speckle morphology by regulating the phosphorylation state of splicing regulatory proteins, and may be involved indirectly in pre-mRNA processing by controlling splicing factor dynamics. The mutations in CDKL5 are a major cause of infantile spasms and early epileptic seizures in female patients, and of a later intractable seizure disorder.
- Validated for use with the Z’-LYTE™ assay
- Available in multiple pack sizes for convenient use
|aa 1 - 498|
|Recombinant, Active, Catalytic|
|CDKs and CHKs|
|Storage Buffer: 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.|