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CCL5 (RANTES) Monoclonal Antibody (VL1), Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen AHC1052
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Descripción
CCL5 (RANTES) is a chemokine gene located on the q-arm of chromosome 17. Chemokines are a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. CCL5, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells, and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. Diseases associated with CCL5 include Human Immunodeficiency Virus Type 1 and Periapical Granuloma.
Especificaciones
| CCL5 (RANTES) | |
| Monoclonal | |
| 1 mg/mL | |
| PBS with no preservative | |
| P13501 | |
| CCL5 | |
| Recombinant human RANTES. | |
| 500 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG2b κ |
| ELISA, Immunohistochemistry (Frozen), Immunoprecipitation, Western Blot | |
| VL1 | |
| Unconjugated | |
| CCL5 | |
| beta-chemokine RANTES; CC chemokine; C-C motif chemokine 5; C-C motif chemokine ligand 5; CCL5; chemokine (C-C motif) ligand 5; D17S136E; EoCP; eosinophil chemotactic cytokine; MGC17164; MuRantes; OTTHUMP00000197106; RANTES; RANTES protein; RANTES(3-68); RANTES(4-68); regulated upon activation normal T-cell expressed and secreted; regulated upon activation, normally T-expressed, and presumably secreted; Scya5; SIS d; SISd; SIS-delta; SISd; small inducible cytokine A5; small inducible cytokine subfamily A (Cys-Cys), member 5; small-inducible cytokine A5; T cell-specific protein P228; T-cell specific protein p288; T-cell-specific protein RANTES; TCP228; Unknown (protein for MGC:127014) | |
| Mouse | |
| Protein A/G | |
| RUO | |
| 6352 | |
| -20°C | |
| Liquid |
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Título del producto
CCL5 (RANTES) Monoclonal Antibody (VL1), Invitrogen™ > 500 μg; Unconjugated
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