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ACROBiosystems Biotinylated Human IL-2 R beta / CD122 Protein, His, Avitag™

Biotinylated Protein

Marca:  ACROBiosystems ILB-H82E3-25ug

Detalles adicionales : Peso : 0.00010kg

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Código de producto. 16477749

  • 391.16€ / 25 microgramos
Fecha estimada de envío: 04-08-2022
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Descripción

Descripción

Interleukin-2 receptor subunit beta (IL2RB) is also known as CD122, which Belongs to the type I cytokine receptor family. Type 4 subfamily. IL2RB contains 1 fibronectin type-III domain. IL2RB / CD122 is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2.

This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 28.2 kDa. The protein migrates as 35-38 kDa and 42-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Especificaciones

Especificaciones

NP_000869.1
28.2 kDa
25 µg
Ala 27 - Asp 239
IL2RB,RP5-1170K4.6,CD122,P70-75
Precision Avi
PBS, pH7.4
HEK293
Human
Powder
>95% as determined by SDS-PAGE
Biotinylated Human IL-2 R beta, His,Avitag (ILB-H82E3) is expressed from human 293 cells (HEK293). It contains AA Ala 27 - Asp 239 (Accession # P14784-1).
-20°C
IL-2 R beta
His Tag and Avi Tag
Less than 1.0 EU / µg by the LAL method.
MABSol™ Biotin Labeled Proteins
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