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ACROBiosystems Biotinylated Human / Cynomolgus / Rhesus macaque CD28 Protein, His, Avitag™
Biotinylated Protein
Marca: ACROBiosystems CD8-H82E5-200ug
Detalles adicionales : Peso : 0.00010kg
Descripción
CD28 homolog (CD28H), also called transmembrane and immunoglobulin domain containing 2 (TMIGD2) and IGPR-1,is encoded by the TMIGD2 gene. CD28H is constitutively expressed on naive T and NK cells. After interaction of CD28 homolog with B7 homologue,the peripheral effector and memory T cells can be activated and proliferated by Akt-dependent signalling cascade. Plays a role in cell-cell interaction, cell migration, and angiogenesis. Through interaction with HHLA2, costimulates T-cells in the context of TCR-mediated activation. Enhances T-cell proliferation and cytokine production via an AKT-dependent signaling cascade.
This protein carries a polyhistidine tag at the C-terminus, followed by an Avi tag. The protein has a calculated MW of 18.7 kDa. The protein migrates as 33-45 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.Especificaciones
NP_006130.1 | |
200 μg | |
Asn 19 - Pro 152 | |
CD28,Tp44 | |
Precision Avi | |
His Tag and Avi Tag | |
Less than 1.0 EU / μg by the LAL method. | |
Powder | |
>90% as determined by SDS-PAGE |
18.7 kDa | |
Biotinylated Human / Cynomolgus / Rhesus macaque CD28, His,Avitag (CD8-H82E5) is expressed from human 293 cells (HEK293). It contains AA Asn 19 - Pro 152 (Accession # P10747-1). | |
-20°C | |
CD28 | |
Human, Cynomolgus Monkey, Rhesus Macaque | |
PBS, pH7.4 | |
HEK293 | |
MABSol™ Biotin Labeled Proteins |