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PDEF Rabbit anti-Human, Polyclonal, Invitrogen™
Rabbit Polyclonal Antibody
Marca: Invitrogen 363600
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Descripción
PDEF (prostate-derived Ets factor) is a 37.5-kDa protein that acts as an androgen-independent transcriptional activator for the PSA (prostate specific antigen) promoter. It also interacts directly with the DNA binding domain of androgen receptor and enhances androgen-mediated activation of the PSA promoter. PDEF was shown to have transcript levels 192-fold higher in the peripheral blood of some breast cancer patients in comparison with normal individuals. PDEF mRNA is also frequently over-expressed in human breast tumors as well as in human ovarian tumors. In ovarian tumors, PDEF expression seems to down-modulate maligt potential, and thus provides a rationale to screen for drugs that induce PDEF expression in epithelial ovarian tumors.
Especificaciones
| PDEF | |
| Polyclonal | |
| Unconjugated | |
| O95238 | |
| SPDEF | |
| Synthetic peptide derived from the internal region of human PDEF (prostate-derived Ets factor). | |
| 100 μg | |
| Primary | |
| Human | |
| Antibody | |
| IgG |
| ELISA, Western Blot | |
| 0.25 mg/mL | |
| SPDEF | |
| SAM pointed domain-containing Ets transcription factor, Prostate epithelium-specific Ets transcription factor, Prostate-specific Ets, Prostate-derived Ets factor, SPDEF, PDEF, PSE | |
| Rabbit | |
| Antigen affinity chromatography | |
| RUO | |
| 25803 | |
| -20°C | |
| Liquid |
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Título del producto
PDEF Rabbit anti-Human, Polyclonal, Invitrogen™ > 100 μg; Unconjugated
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