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LEDGF (Lens Epithelium-Derived Growth Factor) Mouse anti-Human, Unlabeled, Clone: 26, BD
Mouse Monoclonal Antibody
381.00€ - 673.00€
Especificaciones
Antígeno | LEDGF (Lens Epithelium-Derived Growth Factor) |
---|---|
Clon | 26 |
Concentración | 250μg/mL |
Aplicaciones | In vitro Assay, Western Blot |
Clasificación | Monoclonal |
Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
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Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
15866009
|
BD Biosciences
611714 |
50 μg |
381.00€
1 set |
Fecha estimada de envío: 16-05-2024 Inicie sesión para ver el stock |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | ||||
15876009
|
BD Biosciences
611715 |
150 μg |
Este artículo actualmente no está disponible o ha sido discontinuado. Ver la página del producto para posibles alternativas |
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Descripción
p52/p75 proteins were first identified through their interaction with transcriptional factors and splicing factors. p75 is encoded by exons 1-15 and contains 530 amino acids, while the alternatively spliced p52 is encoded by exons 1-9 and contains 333 amino acids. Both p52 and p75 have strong interactions with the VP16 activation domain and with various components of the general transcriptional machinery. p52 is the more active transcription activator and has also been shown to recruit the pre-mRNA splicing factor ASF/SF to sites of active transcription. Interestingly, p52/p75 has also been identified as Lens Epithelium-Derived Growth Factor (LEDGF). In serum free media, LEDGF stimulates the growth and survival of a variety of cells, such as lens epithelial cells, retinal photoreceptor cells, COS7 cells, skin fibroblasts, and keratinocytes. In retinal photoreceptor cells, LEDGF is found in the nucleus where it promotes resistance to serum starvation and thermal stress. Thus, the LEDGF gene encodes splice variants that may regulate gene transcription and mRNA splicing of a variety of proteins that are essential for cell growth and survival.
Host Species: Mouse
Clone: 26
Isotype: IgG1
Species Reactivity [for Features Main]: Human
Immunogen: Human LEDGF aa. 85-188
Immunofluorescence, Western Blotting
Especificaciones
LEDGF (Lens Epithelium-Derived Growth Factor) | |
250μg/mL | |
Monoclonal | |
Mouse | |
Cell Biology | |
Aqueous buffered solution containing BSA, glycerol, and ≤0.09% sodium azide. | |
IgG1 | |
Affinity Purified | |
Lens Epithelium-Derived Growth Factor |
26 | |
In vitro Assay, Western Blot | |
Unconjugated | |
RUO | |
Human | |
Human LEDGF aa. 85-188 | |
Primary | |
Store undiluted at -20°C. |
For Research Use Only.