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CD41 Monoclonal Antibody (MEM-06), PE, Invitrogen™
Mouse Monoclonal Antibody
Marca: Invitrogen MA119648
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Descripción
CD41 (platelet glycoprotein IIb, ITGA2B) is composed of two subunits -120 kDa a, alpha and 23 kDa b, beta- that interact with CD61 in the presence of calcium to form a functional adhesive protein receptor. CD41 is also involved in blood coagulation by mediating platelet aggregation. Upon blood vessel damage, CD41 binds to a variety of proteins including von Willebrand factor, fibrinogen, fibronectin and vitronectin. CD41 is mainly expressed on megakaryocyte-platelet lineage, but generally belongs to the antigens that are expressed during the early stages of hematopoietic differentiation. Diseases associated with CD41 dysfunction include Glansmann Thrombasthenia, and Platelet type-16 bleeding disorder.
Especificaciones
| CD41 | |
| Monoclonal | |
| PE | |
| Itga2b | |
| AI172977; alpha IIb; alphaIIb; alphaIIb protein; BDPLT16; BDPLT2; CD41; CD41B; form 1; form 2; GP IIb; GP2B; GPalpha IIb; GPIIb; GT; GTA; HPA3; integrin alpha 2b; integrin alpha 2b (Cd41b); integrin alpha-IIb; Integrin alpha-IIb heavy chain; Integrin alpha-IIb light chain; Integrin alpha-IIb light chain, form 1; Integrin alpha-IIb light chain, form 2; integrin subunit alpha 2b; integrin subunit alpha IIb; integrin, alpha 2B; integrin, alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex, antigen CD41); ITGA2B; ITGAB; platelet fibrinogen receptor, alpha subunit; platelet glycoprotein IIb; platelet glycoprotein IIb of IIb/II Ia complex; platelet glycoprotein IIb of IIb/IIIa complex; platelet membrane glycoprotein IIb; platelet-specific antigen BAK; PPP1R93; protein phosphatase 1, regulatory subunit 93 | |
| Mouse | |
| Size-exclusion chromatography | |
| RUO | |
| 3674 | |
| 4° C, store in dark, DO NOT FREEZE! | |
| Liquid |
| Flow Cytometry | |
| MEM-06 | |
| PBS with 0.2% BSA and 15mM sodium azide; pH 7.4 | |
| P08514 | |
| Itga2b | |
| Leucocytes from a patient suffering from a LGL type leukaemia. | |
| 100 Tests | |
| Primary | |
| Human | |
| Antibody | |
| IgG1 |
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Título del producto
CD41 Monoclonal Antibody (MEM-06), PE, Invitrogen™ > 100 Tests; PE
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