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Foxp3 Rat anti-Mouse, PE, Clone: MF23, BD
Rat Monoclonal Antibody
248.00€ - 274.00€
Especificaciones
| Antígeno | Foxp3 |
|---|---|
| Clon | MF23 |
| Concentración | 0.2mg/mL |
| Aplicaciones | Flow Cytometry |
| Clasificación | Monoclonal |
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|---|---|---|---|---|---|---|---|---|---|
| Código de producto | Marca | Cantidad | Precio | Cantidad y disponibilidad | |||||
|
15870179
|
BD Biosciences
560414 |
25 μg |
248.00€
cada uno |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | |||||
|
15810179
|
BD Biosciences
560408 |
0.1 mg |
274.00€
cada uno |
Por favor, inicie sesión para comprar este producto. ¿No tiene usuario web? Regístrese hoy mismo. | |||||
Descripción
Foxp3 is a 50-55kDa protein also known as Forkhead box P3, JM2, or IPEX. It is a member of the forkhead or winged helix family of transcription factors and is specifically expressed by T regulatory (Treg) cells. Foxp3 has been reported to be a key regulatory protein for Treg cell development and function. Ectopic expression of Foxp3 in conventional T cells is sufficient to induce suppressive activity, repress the production of cytokines such as IL2 and IFN-γ, and upregulate Treg cell-associated molecules such as CD25, CTLA4 and GITR. It has been found that the mutation of Foxp3 is responsible for “scurfy” mice. When overexpressed, Foxp3 leads to poor T cell proliferation and activation.
Monoclonal antibody MF23 reacts with mouse Foxp3. Immunoblotting with MF23 antibody has confirmed it recognizes an epitope between 1-87 amino acids in the N-terminal domain.
Host Species: Rat
Clone: MF23
Isotype: IgG2b
Species Reactivity: Mouse
Immunogen: Mouse Foxp3 Recombinant Protein
Intracellular Staining
Especificaciones
| Foxp3 | |
| 0.2mg/mL | |
| Monoclonal | |
| Rat | |
| Immunology | |
| Aqueous buffered solution containing ≤0.09% sodium azide. | |
| IgG2b | |
| Affinity Purified |
| MF23 | |
| Flow Cytometry | |
| PE | |
| RUO | |
| Mouse | |
| Mouse Foxp3 Recombinant Protein | |
| Primary | |
| Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze. |
For Research Use Only.
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Título del producto
Foxp3 Rat anti-Mouse, PE, Clone: MF23, BD