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regulator of calcineurin 1, Mouse, Clone: 1B1, Abnova™
Mouse monoclonal antibody raised against a partial recombinant DSCR1.
Marca: Abnova H00001827-M03.100ug
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Descripción
The protein encoded by this gene interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. This gene is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease. Three transcript variants encoding three different isoforms have been found for this gene. [provided by RefSeq
Sequence: MEEVDLQDLPSATIACHLDPRVFVDGLCRAKFESLFRTYDKDITFQYFKSFKRVRINFSNPFSAADARLQLHKTEFLGKEMKLYFAQTLHIGSSHLAPPNEspecificaciones
| regulator of calcineurin 1 | |
| Monoclonal | |
| Unconjugated | |
| PBS with no preservative; pH 7.4 | |
| BC002864 | |
| RCAN1 | |
| DSCR1 (AAH02864, 1 a.a. ∼ 100 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. | |
| 100 μg | |
| Signal Transduction | |
| Primary | |
| Human | |
| Antibody |
| ELISA, Immunofluorescence, Western Blot | |
| 1B1 | |
| Mouse monoclonal antibody raised against a partial recombinant DSCR1. | |
| RCAN1 | |
| ADAPT78/CSP1/DSC1/DSCR1/MCIP1/RCN1 | |
| Mouse | |
| Affinity Purified | |
| RUO | |
| Yes | |
| 1827 | |
| Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. | |
| IgG2b κ |
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Título del producto
regulator of calcineurin 1, Mouse, Clone: 1B1, Abnova™ > 100μg; Unlabeled
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