anti-CD8 alpha FITC, Clone: 53-6.7, Invitrogen™

Descripción

CD8 alpha Monoclonal antibody A18649 from Invitrogen specifically detects CD8 alpha in Mouse samples. It is validated for Flow Cytometry.

The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a corepressor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains, or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain isoforms. Multiple transcript variants encoding different isoforms have been found for this gene.
Host Species: Rat
Cross Reactivity: Mouse
Isotype: IgG2a, κ
Clone: 53-6.7
Immunogen: Mouse CD8a.
Formulation: 25μg Purified Antibody (0.2mg/ml) in PBS, with 0.1% gelatin and 0.09% sodium azide; pH7.2
Synonyms: CD8, Leu-2, MAL, p32, CD8a
Uniprot Accession: P01731
Entrez GeneID: 12525
Gene Symbol: Cd8a
This product detects CD8 alpha in Mouse samples. This product has been successfully used in Flow Cytometry procedures. The immunogen is Mouse CD8a.