X box binding protein 1 (XBP-1) is a key protein in the mammalian unfolded protein response (UPR) that protects the cell against the stress of malfolded proteins in the endoplasmic reticulum (ER). Upon sensing unfolded proteins, an ER transmembrane endonuclease and kinase termed IRE1p is activated and excises an intron from XBP-1 mRNA. The spliced XBP-1 mRNA results in a 371 amino acid protein (XBP-1s) which is then translocated to the nucleus where it binds to the regulatory elements of downstream genes. Together with other UPR transcription factors such as ATF6, XBP-1 stimulates the production ...
Cat # 12837792
100 µg
Cat # 16384525
100 µg
Cat # 12818252
100 µg
Cat # 15794877
0.2mL
Cat # 15724796
0.1 ml
Cat # 15705229
100 ug
Cat # 13471777
100 µL
Cat # 15784776
0.1 mg
Cat # 16040548
100 ug
Cat # 16097206
100 ug
Cat # 15735229
100 ug
Cat # 15725229
100 ug
Cat # 16030517
100 ug
Cat # 16343815
100 µL
Cat # 16802705
20 µL
Cat # 12808252
100 µg
Cat # 11345593
100 µL
Cat # 15763656
0.05mg
Cat # 15736814
25 ug
Cat # 16892695
150 µL
Cat # 16844525
20 µL
Cat # 12877792
100 µg
Cat # 15805803
100 µg
Cat # 15775219
100 ug
Cat # 13490476
100 ug
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk To A Specialist NowIf an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.