This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins. Alternative splicing results in multiple transcript variants encoding the same protein.
p95; p95vav; Proto-oncogene vav; Proto-oncogene vav VAV1 VAV; vav 1 guanine nucleotide exchange factor; vav 1 oncogene; vav oncogene
Cat # 16343115
100 µL
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20 µL
Cat # 15328170
100 µg
Cat # 11547080
100 µL
Cat # 16075597
100 ug
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100 µL
Cat # 16107395
100 µg
Cat # 16895954
150 µL
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100 µL
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100 µg
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100 µL
Cat # 17127278
200 µL
Cat # 16187385
100 µg
Cat # 13278908
100 µL
Cat # 16673755
100 µL
Cat # 16136810
100 uL
Cat # 16046897
100 ug
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