A-Myb is expressed at specific times in reproductive tissues, some neural cells, and a subset of normal and neoplastic B lymphocytes. Both A-Myb and B-Myb are expressed in t(14:18) lymphoma cells where they then inhibit cell arrest and apoptotic signaling. Expression of B-Myb rescues cells from p53-induced G1 phase arrest that is mediated by p21, while A-Myb functions as an anti-apoptotic factor by effectively activating the bcl-2 promoter and thereby up-regulating Bcl-2 expression.
A-Myb; Myb-like protein 1; Myb-related protein A; Myb-related protein A A-Myb Myb-like protein 1 MYBL1 AMYB; v-myb avian myeloblastosis viral oncogene homolog-like 1
Cat # 15991745
100 µL
Cat # 15832784
100 µL
Cat # 15750561
100 µL
Cat # 16613835
100 µL
Cat # 15653715
100 µL
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