The T-cell immune regulator 1 (TCIRG1) is the a3 subunit of the vacuolar-type proton transporting ATPase (V-ATPase), a proton pump in late endosomes and lysosomes that functions in the luminal acidification of these organelles. Genetic defects in the gene encoding this protein a responsible for a severe form of autosomal recessive osteopetrosis, a condition that leads to increased bone density, decreased bone strength, and inflammation in bone tissues. TCIRG1 is also required for the normal secretion of insulin and the bacteria-killing function of macrophages.
ATPase, H+ transporting, 116kD; ATPase, H+ transporting, lysosomal I; ATPase, H+ transporting, lysosomal V0 protein a; OC-116 kDa; osteoclastic proton pump; Osteoclastic proton pump 116 kDa subunit; osteosclerotic; specific 116-kDa vacuolar proton pump subunit; T cell immune response cDNA7 protein; T-cell immune regulator 1; T-cell immune response cDNA 7; T-cell immune response cDNA7 protein; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein a; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 protein A3; T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3; TCIRG1 T-cell immune regulator 1 ATPase H+ transporting lysosomal V0 subunit A3 a3 Stv1 Vph1 Atp6i OC116 OPTB1 TIRC7 ATP6N1C ATP6V0A3 OC-116; TIRC7; V-ATPase 116 kDa subunit a3; V-ATPase 116-kDa; V-ATPase a3; v-H+ATPase subunit a3; V-type proton ATPase 116 kDa subunit a; V-type proton ATPase 116 kDa subunit a isoform 3; V-type proton ATPase 116 kDa subunit a3; vacuolar proton translocating ATPase 116 kDa subunit A; Vacuolar proton translocating ATPase 116 kDa subunit a isoform 3
Cat # 15315351
100 µg
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100 µg
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100 µL
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200 uL
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100 ug
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200 uL
Cat # 16800484
150 µL
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20 µL
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50 µg
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50 µg
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100 µL
Cat # 16172326
50 uL
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