WNK is a serine/threonine kinase that plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. Also, acts as an activator and inhibitor of sodium-coupled chloride cotransporters and potassium-coupled chloride cotransporters respectively. Activates SCNN1A, SCNN1B, SCNN1D, and SGK1. WNK localizes to a segment of kidney involved in salt, potassium, and pH homeostasis, the distal nephron. Mutations in the WNK gene result in Pseudohypaldosteronism and Neuropathy.
SAZD UTP13; transducin (beta)-like 3; Transducin beta-like protein 3; WD repeat-containing protein SAZD; WD-repeat protein SAZD
Cat # 16371215
100 µL
Cat # 16146500
100 uL
Cat # 15527461
100 µL
Cat # 15737871
100 µL
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