The protein encoded by this gene is an activator of MAP3K7/TAK1, which is required for for the IL-1 induced activation of nuclear factor kappaB and MAPK8/JNK. This protein forms a kinase complex with TRAF6, MAP3K7 and TAB1, thus serves as an adaptor linking MAP3K7 and TRAF6. This protein, TAB1, and MAP3K7 also participate in the signal transduction induced by TNFSF11/RANKl through the activation of the receptor activator of NF-kappB (TNFRSF11A/RANK), which may regulate the development and function of osteoclasts.
CHTD2 MAP3K7IP2 TAB-2 TAK1-binding protein 2 TGF-beta-activated kinase 1 and MAP3K7-binding protein 2 TGF-beta-activated kinase 1-binding protein 2 mitogen-activated protein kinase kinase kinase 7-interacting protein 2; mitogen activated protein kinase kinase kinase 7 interacting protein 2; mitogen-activated protein kinase kinase kinase 7 interacting protein 2; Mitogen-activated protein kinase kinase kinase 7-interacting protein 2; TAB-2; Tak1 binding protein 2; TAK1-binding protein 2; TGF-beta-activated kinase 1 and MAP3K7-binding protein 2; TGF-beta-activated kinase 1-binding protein 2
Cat # 13423097
100 µL
Cat # 15395291
100 µg
Cat # 11500441
100 µL
Cat # 17159573
100 µL
Cat # 11305683
100 µL
Cat # 16590102
100 µL
Cat # 16843034
150 µL
Cat # 17189583
100 µL
Cat # 16853034
20 µL
Cat # 17267543
100 µL
Cat # 15965655
100 µg
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