STXBP4 plays a role in the translocation of transport vesicles from the cytoplasm to the plasma membrane. STXBP4 inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2. Stimulation with insulin disrupts the interaction with STX4A, leading to increased levels of SLC2A4 at the plasma membrane. STXBP4 may also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
STX4-interacting protein; STX4-interacting protein syntaxin 4 interacting protein syntaxin 4-interacting protein syntaxin-binding protein 4; syntaxin 4 interacting protein; Syntaxin 4-interacting protein; Syntaxin-binding protein 4
Cat # 15732561
100 µL
Cat # 15702951
100 µL
Cat # 16689314
100 µL
Cat # 11524911
100 µL
Cat # 15722501
100 µL
Cat # 15536932
100 µL
Searching for an antibody we don't offer? We make custom antibodies for specific targets, species and applications.
More than 18,000 custom antibodies created so far.
Talk To A Specialist NowIf an Invitrogen™ antibody doesn’t perform as described on our website or datasheet, we’ll replace the product at no cost to you, or provide you with a credit for a future purchase.*
Get expert recommendations for common problems or connect directly with an on staff expert for technical assistance related to applications, equipment and general product use.