Part of pre- and post-splicing multiprotein mRNP complexes. Involved in numerous pre-mRNA processing events. Promotes constitutive and exonic splicing enhancer (ESE)-dependent splicing activation by bridging together sequence-specific (SR family proteins, SFRS4, SFRS5 and TRA2B/SFRS10) and basal snRNP (SNRP70 and SNRPA1) factors of the spliceosome. Stimulates mRNA 3′-end cleavage independently of the formation of an exon junction complex. Binds both pre-mRNA and spliced mRNA 20-25 nt upstream of exon-exon junctions. Binds RNA and DNA with low sequence specificity and has similar preference for either double- or single-stranded nucleic acid substrates.
160 KD POP101 SRM160 SRRM1; Plenty-of-prolines 101; plenty-of-prolines-101; Ser/Arg-related nuclear matrix protein; serine/arginine repetitive matrix 1; Serine/arginine repetitive matrix protein 1; SR-related nuclear matrix protein of 160 kDa; SRm160
Cat # 16800744
150 µL
Cat # 15729901
100 µL
Cat # 16509341
100 µL
Cat # 15832874
100 µL
Cat # 15948904
100 µL
Cat # 16810744
20 µL
Cat # 17247543
100 µL
Cat # 15876761
100 µL
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