The SCN4B protein modulates channel gating kinetics. Causes negative shifts in the voltage dependence of activation of certain alpha sodium channels, but does not affect the voltage dependence of inactivation By similarity. The protein has been found to be expressed at a high level in dorsal root ganglia, at a lower level in brain, spinal cord, skeletal muscle and heart. Defects in SCN4B are the cause of long QT syndrome type 10 (LQT10) [MIM:611819]. Long QT syndromes are heart disorders characterized by a prolonged QT interval on the ECG and polymorphic ventricular arrhythmias. They cause ...
Cat # 15701521
100 µL
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150 µL
Cat # 16183910
100 uL
Cat # 16648364
100 µL
Cat # 17148273
100 µL
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20 µL
Cat # 15594381
100 µL
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100 µL
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